Products : Contract manufacturing of Microneedles
Designed to match skin needs, with complete testing, with Natureprof (OEM/ODM factory)
Contact Us!If you want a delivery patch that is gentle, safe, easy to use, and traceable, "microneedle patches" are the answer. We design the full range, from skin-dissolving needle bases (such as hyaluronic acid together with PVA/PVP/CMC/chitosan) to gently open microchannels, defining the needle specification to suit the application point (height, density, dissolution time, and feel), along with selecting "necessary and appropriate" actives. We also adjust the patch format to match the brief, such as a targeted acne-spot sheet, an under-eye sheet, or a Hydrogel-forming/Matrix structure design for continuous release and good skin adhesion, for a skin-comfortable use experience. We adjust the adhesive's tack and the patch shape so it does not slip off, with a "clean label" concept selecting options free of fragrance, synthetic color, alcohol, and parabens (as appropriate for the formula and target market). Every formula is backed by test data for both performance and safety, such as dissolution and active release, strength and penetration, product stability, and real-world skin-use evaluation, so you can communicate responsibly on the label and bring genuinely manufacturable, sellable "microneedle patches" to market confidently and transparently.
We provide contract manufacturing of microneedle patches (Microneedles), both as contract manufacturing (OEM) and custom formula design and development (ODM), with a consulting team covering formulation, testing, documentation, and regulatory affairs. We operate under international standards as a factory trusted by leading brands, with controlled quality, full transparency, and traceability at every step. We support production both in Thailand and abroad so your brand is confidently ready to sell from the very first lot.
Microneedles are tiny needle structures on a polymer/biopolymer sheet that, when they contact the skin, open short microchannels, allowing actives to penetrate the skin better than normal application. The key strengths are a skin-comfortable feel, ease of use, and results that can be designed to be "visible," suitable for functional skincare brands, beauty clinics, and development work targeting medical device registration. The classification (cosmetic or medical device) is determined by the formula, product shape, and the claims used, and the Natureprof team is ready to help assess this from the start.
A dissolvable needle structure such as a dissolving microneedle, most commonly a hyaluronic acid microneedle combined with PVA/PVP/CMC/Chitosan, suitable for light- or oxidation-sensitive actives, used for dark spots, wrinkles, acne marks, and targeted work
Suitable when you want very rapid active release or to stimulate the absorption of serum/gel at the desired spot
When in contact with moisture, the structure forms a gel and releases actives consistently, suitable for the under-eye area or areas needing long-lasting nourishment
Dark spots/melasma/freckles: Tranexamic Acid, Niacinamide, vitamin C derivatives | Wrinkles/firming: Peptides (such as Acetyl Hexapeptide-8, Copper Peptide), Adenosine, Retinol (encapsulated/stabilized) | Acne marks-oily skin: Madecassoside, Zinc PCA, designs that support salicylic acid, including specialized work such as a microneedle acne patch - every design supports commercial extension within Natureprof's OEM microneedle and ODM microneedle framework
We start from the real use brief, then design the needle material, actives, and sheet structure to balance "on-target delivery, skin-comfortable feel, and reproducibility."
To confirm quality and safety, we plan comprehensive testing, starting with
Assessing acute skin irritation under systematically controlled time and occlusion conditions
Assessing the risk of causing contact sensitization from repeated contact and a challenge test after a skin rest period
Measuring the strength of the micro-sized needles and the ability to consistently penetrate the epidermis without deforming
Checking the needle dissolution time and the active release rate to confirm delivery as designed
Assessing accelerated and real-time stability, including the suitability of the packaging for product quality
Measuring the amount of active skin permeation and its distribution in the target skin layers, to support data on the mechanism of action
Governing the development, production, validation, documentation, and release processes to align with requirements and support the regulatory/commercial-production pathway
Microneedle patches can fall in either the medical device or cosmeceutical line - define the category clearly from the start to assemble the document set, testing, and the claims that can be made correctly.
Understand the brief and requirements
Design the formula and develop prototypes
Test and refine the formula to be production-ready
Prepare documentation and handle regulatory procedures
Commercial production under a quality system (OEM/ODM)
Delivery, launch, and post-launch support
Ready for Market
Take your "microneedle patches (Microneedles)" brand further
For those who already have a formula or specification, we manufacture to quality standards, issue a Certificate of Analysis (COA) per batch, prepare Thai-English labels, and prepare complete registration filing documents, including export certification documents.
For those who do not yet have a formula, or who want to develop a brand-specific formula, we handle everything from concept, formula, and planning the necessary testing through to defining specifications/labels/regulatory documents, so the product is ready to enter the production line and reach the market immediately.
Send us your initial brief (patch type, use brief/target area, key actives, height-density-dissolution time, skin feel/adhesive tack, patch size-shape, packaging, minimum order quantity, budget, timeline), or schedule an initial consultation with the Natureprof team so we can help design the formula direction and define the brief together, in both OEM Microneedles / ODM Microneedles modes, covering full-service contract manufacturing of microneedle patches through to minimum-order production planning aligned with your business plan.
Innovation from Nature, Ready for Market | Safe • Clean • Effective
Contact the Natureprof Team Today!